Application
Western blot analysis of NGX6 expression in Jurkat whole cell lysate.Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human intestine tissue showing cytoplasmic staining.| Product Name | NGX6 Antibody (X-23) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against NGX6 of human origin |
| Modification Notes | Nasopharyngeal carcinoma (NPC) is a common cancer in South China, but is not usually found in other parts of the world. NPC is characterized by orofacial pain and altered nerve sensation as well as a tendency to metastasize. The NPC associated gene 6 (NGX6) is located at a chromosomal location with a high frequency of loss of heterozygosity (LOH). The NGX6 protein contains an epidermal growth factor-like domain and a cytoplasmic region, both of which play a role in modulating cell adhesion. The cytoplasmic domain also functions to regulate growth, proliferation and migration through its association with Ezrin and the ability of the NGX6 protein to downregulate Ezrin expression. NGX6 also inhibits transcriptional activation of ∫-catenin/TCF/LEF in the Wnt signaling pathway by negatively regulating the nuclear translocation of ∫-catenin. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of NGX6 of mouse, rat, human and canine origin by WB, IP, IF, IHC(P) and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against NGX6 of human origin |
|---|---|
| Tissue Specificity | raised against NGX6 of human origin |
| Entrez Gene | 51754 |
|---|
Application
Western blot analysis of NGX6 expression in Jurkat whole cell lysate.
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human intestine tissue showing cytoplasmic staining.| Application Notes | recommended for detection of NGX6 of mouse, rat, human and canine origin by WB, IP, IF, IHC(P) and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
