Application
Western blot analysis of CYP4A22 expression in non-transfected 293T: (A), human CYP4A22 transfected 293T: (B) and Jurkat (C) whole cell lysates.Application
Western blot analysis of CYP4A22 expression in Jurkat whole cell lysate.Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic staining.| Product Name | CYP4A22 Antibody (S-19) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against CYP4A22 of human origin |
| Modification Notes | Cytochrome P450 proteins are heme-thiolate monooxygenases that mediate NADPH-dependent electron transport and function to oxidize a variety of structurally unrelated compounds, including steroids, fatty acids and xenobiotics. Specifically, Cytochrome P450s are responsible for metabolizing arachidonic acid to hydroxyeicosatetraenoic acid (a regulator of blood pressure) and epoxyeicosatrienoic acid (a molecule involved in signaling events). CYP4A22 (cytochrome P450, family 4, subfamily A, polypeptide 22) is a 519 amino acid protein that is encoded by a gene located within a cluster of Cytochrome P450 genes on chromosome 1. Sharing 96% sequence similarity with CYP4A11 (a related family member), CYP4A22 is thought to play a role in fatty acid metabolism, possibly mediating kidney function and blood pressure. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| recommended for detection of CYP4A22 of human origin by WB, IP, IF, IHC(P) and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against CYP4A22 of human origin |
|---|---|
| Tissue Specificity | raised against CYP4A22 of human origin |
| Entrez Gene | 284541 |
|---|
Application
Western blot analysis of CYP4A22 expression in non-transfected 293T: (A), human CYP4A22 transfected 293T: (B) and Jurkat (C) whole cell lysates.
Application
Western blot analysis of CYP4A22 expression in Jurkat whole cell lysate.
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human kidney tissue showing cytoplasmic staining.| Application Notes | recommended for detection of CYP4A22 of human origin by WB, IP, IF, IHC(P) and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
