Application
Western blot analysis of ATP6AP1L expression in Hep G2 whole cell lysate.| Product Name | ATP6AP1L Antibody (P-19) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against ATP6AP1L of human origin |
| Modification Notes | Vacuolar-type H(+)-ATPase (V-ATPase) is a multisubunit enzyme responsible for acidification of eukaryotic intracellular organelles. V-ATPases pump protons against an electrochemical gradient, while F-ATPases reverse the process, thereby synthesizing ATP. ATP6AP1L, also known as V-type proton ATPase subunit S1-like protein, is a 224 animo acid single-pass membrane protein that belongs to the vacuolar ATPase subunit S1 family. The gene that encodes ATP6AP1L maps to human chromosome 5q14.2. With 181 million base pairs encoding around 1,000 genes, chromosome 5 is about 6% of human genomic DNA. It is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5 associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| recommended for detection of ATP6AP1L of human origin by WB, IP and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against ATP6AP1L of human origin |
|---|---|
| Tissue Specificity | raised against ATP6AP1L of human origin |
| Entrez Gene | 92270 |
|---|
Application
Western blot analysis of ATP6AP1L expression in Hep G2 whole cell lysate.| Application Notes | recommended for detection of ATP6AP1L of human origin by WB, IP and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
