Application
Western blot analysis of ZNF839 expression in Hep G2 whole cell lysate.| Product Name | ZNF839 Antibody (B-22) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against ZNF839 of human origin |
| Modification Notes | C14orf131, also known as ZNF839, is an 811 amino acid protein that contains one C2H2-type zinc finger. The gene encoding C14orf131 localizes to chromosome 14 and, due to alternative splicing events, four C14orf131 isoforms are expressed. Chromosome 14 contains about 700 genes and 106 million base pairs and makes up about 3.5% of human cellular DNA. Chromosome 14 encodes the presinilin 1 (PSEN1) gene, which is one of the three key genes associated with the development of Alzheimer's disease. The SERPINA1 gene is located on chromosome 14 and when defective leads to the genetic disorder å1-antitrypsin deficiency. This disorder is characterized by severe lung complications and liver dysfunction. Notably, the immunoglobulin heavy chain locus is found on chromosome 14 and has been identified as a fusion with the chromosome 19 encoded protein BCL3 in the (14;19) translocations found in a variety of B cell malignancies. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| recommended for detection of ZNF839 of human origin by WB, IP and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against ZNF839 of human origin |
|---|---|
| Tissue Specificity | raised against ZNF839 of human origin |
| Entrez Gene | 55778 |
|---|
Application
Western blot analysis of ZNF839 expression in Hep G2 whole cell lysate.| Application Notes | recommended for detection of ZNF839 of human origin by WB, IP and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
