| Product Name | GPR180 Antibody (N-20) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping near the N-terminus of GPR180 of human origin |
| Modification Notes | G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins that play a role in many different stimulus-response pathways. GPR signaling is an evolutionarily ancient mechanism used by all eukaryotes to sense environmental stimuli and mediate cell-cell communication. G protein-coupled receptors provide attractive targets for drug therapy due to the sheer size and diversity of ligands within this receptor family. GPR180, also designated ITR (intimal thickness-related receptor), is a 440 amino acid protein that is highly expressed in vascular smooth muscle cells where it has been shown to increase the thickness of blood vessel intima. Due to its role in vascular remodeling, GPR180 may represent a potential target for development of drugs in the prevention of vascular restenosis, a condition that is common after percutaneous transluminal coronary angioplasty (PTCA). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of GPR180 of m and h origin by WB, IF and ELISA non cross-reactive with other GPR family members also reactive with additional species, including canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the N-terminus of GPR180 of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the N-terminus of GPR180 of human origin |
| Entrez Gene | 160897 |
|---|
| Application Notes | recommended for detection of GPR180 of m and h origin by WB, IF and ELISA non cross-reactive with other GPR family members also reactive with additional species, including canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
