Application
Western blot analysis of ACCN5 expression in non-transfected: (A) and human ACCN5 transfected: (B) 293 whole cell lysates.| Product Name | ACCN5 Antibody (Y-16) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against ACCN5 of human origin |
| Modification Notes | ACCN5 (amiloride-sensitive cation channel 5), also known as INAC (intestine Na+ channel) or HINAC (human intestine Na+ channel), is a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. DEG/ENaC superfamily members are amiloride-sensitive sodium channels that contain intracellular N- and C-termini, two hydrophobic transmembrane regions and a cysteine-containing extracellular loop. Localizing to the cell membrane, ACCN5 is a multi-pass membrane protein that is expressed in small intestine, jejunum and duodenum. ACCN5 is also expressed at low levels in rectum and testis. Existing as a homo- or heterotetramer, ACCN5 functions as a Na+-selective cation channel that, characteristic of its family, can be inhibited by amiloride. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| recommended for detection of ACCN5 of human origin by WB, IP and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against ACCN5 of human origin |
|---|---|
| Tissue Specificity | raised against ACCN5 of human origin |
| Entrez Gene | 51802 |
|---|
Application
Western blot analysis of ACCN5 expression in non-transfected: (A) and human ACCN5 transfected: (B) 293 whole cell lysates.| Application Notes | recommended for detection of ACCN5 of human origin by WB, IP and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
