Application
Western blot analysis of LRRC15 expression in IMR-32 (A), SH-SY5Y (B) and JAR (C) whole cell lysates.| Product Name | LRRC15 Antibody (L-20) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an extracellular domain of LRRC15 of human origin |
| Modification Notes | Leucine-rich repeats (LRRs) are 20-29 amino acid motifs that mediate protein-protein interactions. The primary function of these motifs is to provide a versatile structural framework for the formation of these protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutations in genes encoding LRR-containing proteins. The leucine-rich repeat-containing protein 15 (LRRC15, also designated LIB) is a 581 amino acid protein that contains 15 LRR repeats and is involved in cell-cell and/or -extracellular matrix interactions. LRRC15 is frequently overexpressed in multiple tumor types, most notably breast carcinoma. It is also associated with the pathogenesis of Alzheimer’s disease. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of LRRC15 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other LRRC family members also reactive with additional species, including equine, canine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an extracellular domain of LRRC15 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an extracellular domain of LRRC15 of human origin |
| Entrez Gene | 131578 |
|---|
Application
Western blot analysis of LRRC15 expression in IMR-32 (A), SH-SY5Y (B) and JAR (C) whole cell lysates.| Application Notes | recommended for detection of LRRC15 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other LRRC family members also reactive with additional species, including equine, canine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
