| Product Name | SLC26A7 Antibody (N-14) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping near the N-terminus of SLC26A7 of human origin |
| Modification Notes | SLC26A7 (solute carrier family 26, member 7) is a 656 amino acid multi-pass membrane protein that belongs to the SLC26 family of sulfate/anion transporter proteins. Members of this family are structurally well conserved, yet they have markedly different tissue expression patterns. SLC26 family members can mediate the electroneutral exchange of Cl(-) for HCO(-)(3) across the plasma membrane of mammalian cells. SLC26A7 shares 30% identity with SLC26A2. SLC26A7 is predicted to contain 12 transmembrane regions with internal N- and C-termini. Playing a major role in gastric acid secretion, SLC26A7 is active at both alkaline and acidic pH. Expressed in the cytoplasm in recycling endosomes of medullary collecting duct cells and in acid-secreting gastric parietal cells, SLC26A7 is targeted to the basolateral membrane in hypertonicity and potassium depletion. Existing as two alternatively spliced isoforms, the SLC26A7 gene is conserved in dog, cow, mouse, rat, chicken and A.thaliana, and maps to human chromosome 8q21.3. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of SLC26A7 of mouse, rat and human origin by WB, IF and ELISA also reactive with additional species, including equine, canine and bovine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the N-terminus of SLC26A7 of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the N-terminus of SLC26A7 of human origin |
| Entrez Gene | 115111 |
|---|
| Application Notes | recommended for detection of SLC26A7 of mouse, rat and human origin by WB, IF and ELISA also reactive with additional species, including equine, canine and bovine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
