Application
Western blot analysis of pyridoxal phosphatase expression in non-transfected: (A) and human pyridoxal phosphatase transfected: (B) 293T whole cell lysates.| Product Name | pyridoxal phosphatase Antibody (H-40) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 158-197 mapping within an internal region of pyridoxal phosphatase of human origin |
| Modification Notes | Pyridoxal phosphatase (PLPase) is an autoantigen comprising 296 amino acids. PLPase catalyzes the dephosphorylation of pyridoxal 5'-phosphate (the active form of vitamin B6) and exhibits a high level of expression various parts of the central nervous system, especially the brain. PLPase activity is catalyzed by haloacid dehalogenase (HAD), and it is is the cofactor of both aromatic L-amino acid decarboxylase and glutamate decarboxylase. Autoantibodies against pyridoxal phosphatase show a strong correlation with certain types of cancer. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of pyridoxal phosphatase of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including bovine, canine and equine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 158-197 mapping within an internal region of pyridoxal phosphatase of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 158-197 mapping within an internal region of pyridoxal phosphatase of human origin |
Application
Western blot analysis of pyridoxal phosphatase expression in non-transfected: (A) and human pyridoxal phosphatase transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of pyridoxal phosphatase of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including bovine, canine and equine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
