epitope mapping within an internal region of APRG1 of human origin
Modification Notes
APRG1 (AP20 region protein 1) is a 170 amino acid single-pass membrane protein that exists as 3 alternatively spliced isoforms. APRG1 isoform 1 is highly expressed in placenta and pancreas, while isoform 2 is mainly expressed in kidney. The gene encoding APRG1 maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci. Key tumor suppressing genes on chromosome 3 include those that encode the apoptosis mediator RASSF1, the cell migration regulator HYAL1 and the angiogenesis suppressor SEMA3B. Marfan syndrome, porphyria, von Hippel-Lindau syndrome, osteogenesis imperfecta and Charcot-Marie-Tooth disease are a few of the numerous genetic diseases associated with chromosome 3.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of APRG1 of human origin by WB, IF and ELISA:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of APRG1 of human origin
Tissue Specificity
epitope mapping within an internal region of APRG1 of human origin