| Product Name | CEP192 Antibody (N-17) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping at the N-terminus of CEP192 of human origin |
| Modification Notes | Centrosomes are the major microtubule-organizing centers of mammalian cells. They are composed of a centriole pair and surrounding microtubule-nucleating material termed pericentriolar material (PCM). Bipolar mitotic spindle assembly relies on two intertwined processes: centriole duplication and centrosome maturation. Failure to properly orchestrate centrosome duplication and maturation is subsequently linked to spindle defects, which can result in aneuploidy and promote cancer progression. The human homolog of the C. elegans and D. melanogaster protein SPD-2 is CEP192 (centrosomal protein of 192 kDa), an integral regulator of PCM recruitment, centrosome maturation centriole duplication. CEP192 forms a scaffold upon which proteins involved in microtubule nucleation and spindle assembly become active during mitosis. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of CEP192 of human origin by WB, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping at the N-terminus of CEP192 of human origin |
|---|---|
| Tissue Specificity | epitope mapping at the N-terminus of CEP192 of human origin |
| Entrez Gene | 55125 |
|---|
| Application Notes | recommended for detection of CEP192 of human origin by WB, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
