| Product Name | Vps36 Antibody (y-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 267-566 mapping at the C-terminus of Vps36 of Saccharomyces cerevisiae origin |
| Modification Notes | Vacuolar protein sorting mutant 36 (VPS36), a class E VPS protein identified in yeast, is an important component of the trafficking pathway of proteins from the Golgi to the endosome. VPS36 functions as a member of the ESCRT-II complex that transiently associates with the endosomal membrane to sort ubiquitinated endosomal membrane proteins as part of a coordinated cascade of events to select multivesicular body cargoes for delivery to the lumen of the lysosome. VPS36 involvement in post-Golgi endosomal-vacuolar protein sorting is indicated by the fact that VPS mutants secrete unprocessed insulin-containing fusion protein (ICFP), induce a stress-response element and repress pheromone-dependent transcription. VPS36 suppresses the phenotype of targeting defective plasma membrane ATPase (Pma1) by allowing mutant Pma1 to regain movement into the plasma membrane. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Vps36 of Saccaromyces cerevisiae origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 267-566 mapping at the C-terminus of Vps36 of Saccharomyces cerevisiae origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 267-566 mapping at the C-terminus of Vps36 of Saccharomyces cerevisiae origin |
| Application Notes | recommended for detection of Vps36 of Saccaromyces cerevisiae origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
