Application
Western blot analysis of Visual Arrestin expression in non-transfected: (A) and human Visual Arrestin transfected: (B) 293 whole cell lysates.Application
Western blot analysis of Visual Arrestin expression in non-transfected: (A) and mouse Visual Arrestin transfected: (B) 293T whole cell lysates and mouse eye tissue extract (C).Application
Western blot analysis of Visual Arrestin expression in mouse eye (A) and rat eye (B) tissue extracts.| Product Name | Visual Arrestin Antibody (H-90) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 316-405 mapping at the C-terminus of Visual Arrestin of human origin |
| Modification Notes | Members of the Arrestin/∫-Arrestin protein family are thought to participate in agonist-mediated desensitization of G protein-coupled receptors, and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters or sensory signals. Visual Arrestin, also known as Arrestin, retinal S-antigen or S-Arrestin, is a major soluble photoreceptor protein that regulates light-dependent signal transduction through G protein-coupled receptor (rhodopsin) activation. Visual Arrestin is expressed in retinal photoreceptor cells and the pineal gland. Visual Arrestin is the major pathogenic autoantigen in inflammatory eye disease, such as uveoretinitis and Oguchi disease, a rare autosomal recessive form of night blindness. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Visual Arrestin of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 316-405 mapping at the C-terminus of Visual Arrestin of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 316-405 mapping at the C-terminus of Visual Arrestin of human origin |
| Entrez Gene | 6295 |
|---|
Application
Western blot analysis of Visual Arrestin expression in non-transfected: (A) and human Visual Arrestin transfected: (B) 293 whole cell lysates.
Application
Western blot analysis of Visual Arrestin expression in non-transfected: (A) and mouse Visual Arrestin transfected: (B) 293T whole cell lysates and mouse eye tissue extract (C).
Application
Western blot analysis of Visual Arrestin expression in mouse eye (A) and rat eye (B) tissue extracts.| Application Notes | recommended for detection of Visual Arrestin of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
