Application
Western blot analysis of CYP2F2 expression in mouse lung tissue extract.| Product Name | CYP2F2 Antibody (M-74) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 189-262 mapping within an internal region of CYP2F2 of mouse origin |
| Modification Notes | CYP2F2 (cytochrome P450 2F2) is a murine-specific membrane-bound protein usually localized to the endoplasmic reticulum membrane. Cytochromes, which are incredibly polymorphic, generally catalyze redox reactions. CYP2F1 is a lung-specific cytochrome P450 (pigment at 450 nm) that is involved in metabolizing potentially carcinogenic pneumotoxins. Its polymorphic nature likely has an impact on the sensitivity of an individual to such toxins. Specifically within Clara cells, CYP2F2 converts Napthalene (commonly found in mothballs) to a glutathione-dihydronapthalene conjugate which is implicated in causing necrosis in Clara cells. Napthalene has a similar chemical structure to that of Skatole, which has been used to supplement flavor in cigarettes. CYP2F2 is the murine homolog of human CYP2F1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of CCYP2F2 of mouse and rat origin by WB, IP, IF and ELISA may cross-react, to a lesser extent, with CYP2F1 of human origin: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 189-262 mapping within an internal region of CYP2F2 of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 189-262 mapping within an internal region of CYP2F2 of mouse origin |
| Entrez Gene | 1572 |
|---|
Application
Western blot analysis of CYP2F2 expression in mouse lung tissue extract.| Application Notes | recommended for detection of CCYP2F2 of mouse and rat origin by WB, IP, IF and ELISA may cross-react, to a lesser extent, with CYP2F1 of human origin: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
