Application
Western blot analysis of TMP21 expression in non-transfected: (A) and mouse TMP21 transfected: (B) 293T whole cell lysates.| Product Name | TMP21 Antibody (H-65) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 41-105 mapping near the N-terminus of TMP21 of human origin |
| Modification Notes | TMP21 (21 kDa transmembrane-trafficking protein), also known as TMED10 (transmembrane emp24 domain-containing protein 10), Tmp-21, S31I125, S31III125, p23 or p24∂, is a member of the EMP24/GP25L/p24 cargo family of proteins that regulates vesicular trafficking in the early secretory pathway. TMP21 is a ubiquitously expressed single-pass type I membrane protein localizing to the Golgi cisternae and the plasma membrane. It contains one GOLD (Golgi dynamics) domain and participates in protein transport and quality control between the endoplasmic reticulum (ER) and the Golgi complex. In addition, TMP21 is a component of the heteromeric secretase complex (or Presenilin complex) and functions to regulate the ©-secretase activity. Two isoforms, namely TMP21-I and TMP21-II, exist for this protein. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of TMP21 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 41-105 mapping near the N-terminus of TMP21 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 41-105 mapping near the N-terminus of TMP21 of human origin |
| Entrez Gene | 10972 |
|---|
Application
Western blot analysis of TMP21 expression in non-transfected: (A) and mouse TMP21 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of TMP21 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
