Application
Western blot analysis of Liprin α1 expression in BT-20 whole cell lysate.| Product Name | Liprin α1 Antibody (H-89) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 475-563 mapping within an internal region of Liprin α1 of human origin |
| Modification Notes | Liprins interact with members of the leukocyte common antigen-related (LAR) family of transmembrane protein tyrosine phosphatases, which are implicated in axon guidance and mammary gland development. Liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR phosphatases. Based on sequence similarities and binding characteristics, liprins are subdivided into å and ∫ liprins. Both å and ∫ liprins homodimerize via their N-terminal, coiled-coil regions. Liprin å1 is a ubiquitously expressed protein that interacts with the tumor suppressor ING4 to regulate cell migration and possibly prevent metastasis. The interaction between LAR and Liprin å1 can be weakened by treatment of Liprin å1 with calf intestinal phosphatase. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Liprin α1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine and canine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 475-563 mapping within an internal region of Liprin &alpha 1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 475-563 mapping within an internal region of Liprin α1 of human origin |
| Entrez Gene | 8500 |
|---|
Application
Western blot analysis of Liprin α1 expression in BT-20 whole cell lysate.| Application Notes | recommended for detection of Liprin α1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine and canine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
