epitope mapping within a cytoplasmic domain of SLITRK3 of human origin
Modification Notes
The leucine-rich (LRR) repeat is a 20-30 amino acid motif that forms a hydrophobic å/∫ horseshoe fold, allowing it to accommodate several leucine residues within a tightly packed core. All LRR repeats contain a variable segment and a highly conserved segment, the latter of which accounts for 11 or 12 residues of the entire LRR motif. SLITRK3 (SLIT and NTRK-like family, member 3) is a 977 amino acid single-pass type I membrane protein that contains 20 LRR repeats and belongs to the SLITRK family. Expressed at highest levels in cerebral cortex, SLITRK3 is also found in adult and fetal neural tissues and some astrocytic brain tumors. SLITRK3 functions to suppress neurite outgrowth and plays a role in the regulation of neuronal function. SLITRK3 is encoded by a gene that maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of SLITRK3 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other SLITRK family members also reactive with additional species, including equine, canine and porcine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within a cytoplasmic domain of SLITRK3 of human origin
Tissue Specificity
epitope mapping within a cytoplasmic domain of SLITRK3 of human origin
Western blot analysis of SLITRK3 expression in HeLa whole cell lysate.
Application Notes
recommended for detection of SLITRK3 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other SLITRK family members also reactive with additional species, including equine, canine and porcine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.