| Product Name | SLITRK1 Antibody (H-190) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 261-450 mapping within an N-terminal extracellular domain of SLITRK1 of human origin |
| Modification Notes | SLITRK family proteins are integral membrane proteins that have a C-terminal domain that is partially similar to TRK neurotrophin receptor proteins and two leucine-rich repeat (LRR) domains that are similar to those of SLIT proteins. SLIT and NTRK-like protein 1 (SLITRK1) is a 696-amino acid protein that contains 13 LRRs. SLITRK1 enhances neurite outgrowth and is expressed predominantly in the frontal lobe of the cerebral cortex of the brain, but is also expressed in some astrocytic brain tumors such as gangliogliomas, gliobastomas, astrocytomas, oligodendrogliomas and primitive neuroectodermal tumors. In a small percentage of affected individuals, mutations in the SLITRK1 gene may be an indirect cause of Tourette's syndrome (TS), a genetically influenced developmental neuropsychiatric disorder characterized by chronic motor and vocal tics. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of SLITRK1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 261-450 mapping within an N-terminal extracellular domain of SLITRK1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 261-450 mapping within an N-terminal extracellular domain of SLITRK1 of human origin |
| Entrez Gene | 114798 |
|---|
| Application Notes | recommended for detection of SLITRK1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
