Application
Western blot analysis of ARHGAP20 expression in rat brain tissue extract.| Product Name | ARHGAP20 Antibody (S-24) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of ARHGAP20 of mouse, rat and human origin by WB, IP, IF and IHC(P) |
| Modification Notes | GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins. ARHGAP20 (Rho GTPase activating protein 20), also known as KIAA1391, is a 1,191 amino acid protein that contains one PH domain, one Ras-associating domain and one Rho-GAP domain. Expressed primarily in brain, but also present in lymph nodes and fetal liver, ARHGAP20 functions as a GTPase-activating protein for Rho-type GTPases, effectively converting Rho-type GTPases to an inactive, GDP-bound state. ARHGAP20 exists as multiple isoforms that are produced via alternative splicing. Chromosomal aberrations involving the ARHGAP20 gene are thought to be a cause of B-cell chronic lymphocytic leukemia (B-CLL). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHC |
| WB:1:500~1:2000 IP:1:100~1:500 IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of ARHGAP20 of mouse rat and human origin by WB IP IF and IHC(P) |
|---|---|
| Tissue Specificity | recommended for detection of ARHGAP20 of mouse, rat and human origin by WB, IP, IF and IHC(P) |
| Entrez Gene | 57569 |
|---|
Application
Western blot analysis of ARHGAP20 expression in rat brain tissue extract.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
