| Product Name | BRS-3 Antibody (H-58) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 27-84 mapping near the N-terminus of Bombesin Receptor Subtype-3 of human origin |
| Modification Notes | Bombesin receptor subtype-3 (BRS-3) is an integral membrane protein belonging to the G protein-coupled receptor 1 family. The gene encoding for the BRS-3 protein maps against chromosome Xq26.3. BRS-3 is important in sperm cell division, maturation and function. Its actions are mediated by G protein interactions which activate a phosphatidylinositol-calcium second messenger system. BRS-3 is expressed in germ cells in testis and in lung carcinoma cells. Unlike other bombesin proteins, BRS-3 does not seem to be detected in the gut and central nervous system, but has been found in rat gastrointestinal tract. Mice lacking the gene encoding for BRS-3 develop obesity suggesting that BRS-3 may play a role in the regulation of plasma Insulin concentration. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Bombesin Receptor Subtype-3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 27-84 mapping near the N-terminus of Bombesin Receptor Subtype-3 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 27-84 mapping near the N-terminus of Bombesin Receptor Subtype-3 of human origin |
| Application Notes | recommended for detection of Bombesin Receptor Subtype-3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
