Application
Western blot analysis of SerRS expression in human liver (A) and human hippocampus (B) tissue extracts.| Product Name | SerRS Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 57-355 mapping within an internal region of SerRS of human origin |
| Modification Notes | The fidelity of protein synthesis requires efficient discrimination of amino acid substrates by aminoacyl-tRNA synthetases. Aminoacyl-tRNA synthetases function to catalyze the aminoacylation of tRNAs by their corresponding amino acids, thus linking amino acids with tRNA-contained nucleotide triplets. SerRS (seryl-tRNA synthetase), also known as SERS or SARS, is a 514 amino acid member of the class-II aminoacyl-tRNA synthetase family that catalyzes the tRNASer-serine aminoacylation reaction. Localized to the cytoplasm, SerRS exists as a homodimer and contains a core catalytic domain and a tRNA-binding domain. In addition to recognizing and serylating tRNASer, SerRS can also recognize and serylate tRNASec (tRNAselenocysteine). Via this interaction, SerRS is implicated in selenocysteine (Sec) biosynthesis. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of SerRS of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 57-355 mapping within an internal region of SerRS of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 57-355 mapping within an internal region of SerRS of human origin |
| Entrez Gene | 6301 |
|---|
Application
Western blot analysis of SerRS expression in human liver (A) and human hippocampus (B) tissue extracts.| Application Notes | recommended for detection of SerRS of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
