Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human nasopharynx tissue showing nuclear and cytoplasmic staining of respiratory epithelial cells.Application
Western blot analysis of IL-33 expression in C6 whole cell lysate.| Product Name | IL-33 Antibody (M-266) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-266 representing full length IL-33 of mouse origin |
| Modification Notes | The interleukins (ILs) are a broad family of well characterized cytokines, primarily of hematopoietic cell origin. They are secreted by immune cells (mainly macrophages, B-cells or T-cells) that regulate a wide range of immune system functions. The specific functions of different interleukins vary from the regulation of inflammatory and immune responses to the regulation of other interleukins. IL-33 (interleukin 33), also known as DVS27, IL1F11, C9orf26 or NF-HEV, is a 270 amino acid secreted protein that belongs to the IL family. Expressed in tonsils and lymph nodes, IL-33 functions as a cytokine that is stimulated via interaction with ST2, an association that recruits a variety of proteins, including MyD88, IRAK-1 and TRAF6, and can also induce T helper-associated cytokine activity. IL-33 plays a role in the survival and adhesion of mast cells and may be involved in the control of endothelial cell activation. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of IL-33 of mouse and rat origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-266 representing full length IL-33 of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-266 representing full length IL-33 of mouse origin |
| Entrez Gene | 77125 |
|---|
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human nasopharynx tissue showing nuclear and cytoplasmic staining of respiratory epithelial cells.
Application
Western blot analysis of IL-33 expression in C6 whole cell lysate.| Application Notes | recommended for detection of IL-33 of mouse and rat origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
