| Product Name | FMO1 Antibody (H-43) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 286-328 mapping within an internal region of FMO1 of human origin |
| Modification Notes | The Flavin containing monooxygenase family consists of five gene products, FMO1-5, that are major enzymatic oxidants involved in the metabolism of various therapeutics. FMO1, also known as dimethylaniline oxidase 1 or dimethylaniline monooxygenase (N-oxide-forming) 1, is a 532 amino acid protein localized to the microsome and endoplasmic reticulum membranes. In human fetuses, the FMO1 gene is expressed in the liver, but shortly after birth, expression is switched off. However, the gene continues to be expressed in adult kidney and, to a lesser extent, in intestine. In all other mammals, the FMO1 gene continues to be expressed in liver after birth. Functionally, FMO1 is involved in the oxidative metabolism of a variety of xenobiotics, such as drugs and pesticides, primarily by catalyzing the N-oxygenation of secondary and tertiary amines. The gene encoding FMO1 is located on chromosome 1q24.3. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of FMO1 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other FMO family members also reactive with additional species, including equine and canine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 286-328 mapping within an internal region of FMO1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 286-328 mapping within an internal region of FMO1 of human origin |
| Entrez Gene | 2326 |
|---|
| Application Notes | recommended for detection of FMO1 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other FMO family members also reactive with additional species, including equine and canine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
