Application
Western blot analysis of UROC1 expression in non-transfected: (A) and mouse UROC1 transfected: (B) 293T whole cell lysates.| Product Name | UROC1 Antibody (C-14) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping at the C-terminus of UROC1 of human origin |
| Modification Notes | UROC1, also known as urocanate hydratase, is a 676 amino acid protein that is involved in histidine metabolism. Defects in the gene encoding UROC1 result in urocanic aciduria, which is characterized by learning difficulties, mental retardation, short stature and intermittent ataxia. The UROC1 gene resides on chromosome 3, which contains about 214 million bases encoding over 1,100 genes. Notably, there is a chemokine receptor gene cluster and a variety of human cancer related loci on chromosome 3. Particular regions of the chromosome 3 short arm are deleted in many types of cancer cells. Key tumor suppressing genes on chromosome 3 encode apoptosis mediator RASSF1, cell migration regulator HYAL1 and angiogenesis suppressor SEMA3B. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of UROC1 of human and, to a lesser extent, mouse origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping at the C-terminus of UROC1 of human origin |
|---|---|
| Tissue Specificity | epitope mapping at the C-terminus of UROC1 of human origin |
| Entrez Gene | 131669 |
|---|
Application
Western blot analysis of UROC1 expression in non-transfected: (A) and mouse UROC1 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of UROC1 of human and, to a lesser extent, mouse origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
