Application
Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear localization.Application
Western blot analysis of NUDT18 expression in non-transfected 293: (A), human NUDT18 transfected 293: (B) and HeLa (C) whole cell lysates.| Product Name | NUDT18 Antibody (G-14) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of NUDT18 of human origin |
| Modification Notes | NUDT18 (nudix (nucleoside diphosphate linked moiety X)-type motif 18) is a 323 amino acid protein that contains one nudix hydrolase domain and belongs to the nudix hydrolase family. Using magnesium or manganese as cofactors, NUDT18 is thought to mediate the hydrolysis of select nucleoside diphosphate derivatives. Multiple isoforms of NUDT18 exist due to alternative splicing events. The gene encoding NUDT18 maps to human chromosome 8, which encodes over 800 genes and is associated with a variety of diseases and malignancies. Schizophrenia, bipolar disorder, Trisomy 8, Pfeiffer syndrome, congenital hypothyroidism, Waardenburg syndrome and some leukemias and lymphomas are thought to occur as a result of defects in specific genes that maps to chromosome 8. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of NUDT18 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of NUDT18 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of NUDT18 of human origin |
| Entrez Gene | 79873 |
|---|
Application
Immunofluorescence staining of methanol-fixed HeLa cells showing nuclear localization.
Application
Western blot analysis of NUDT18 expression in non-transfected 293: (A), human NUDT18 transfected 293: (B) and HeLa (C) whole cell lysates.| Application Notes | recommended for detection of NUDT18 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
