recommended for detection of NUDT17 of human origin by WB, IP and ELISA
Modification Notes
NUDT17 (nudix (nucleoside diphosphate linked moiety X)-type motif 17) is a member of the Nudix hydrolase family of pyrophosphatases. Nudix hydrolases contain a characteristic Nudix domain and are responsible for catalyzing the hydrolysis of nucleoside diphosphate derivatives. NUDT17 is a 328 amino acid protein that uses magnesium or manganese as a cofactor. The gene encoding NUDT17 maps to human chromosome 1, the largest human chromosome spanning about 260 million base pairs and making up 8% of the human genome. Approximately 3,000 genes are located on chromosome 1, which include several disease genes. Notably, the rare aging disease Hutchinson-Gilford progeria is associated with the LMNA gene which encodes lamin A as well as Stickler syndrome, Parkinsons, Gaucher disease and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers including head and neck cancer, malignant melanoma and multiple myeloma.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPELISA
WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
recommended for detection of NUDT17 of human origin by WB IP and ELISA
Tissue Specificity
recommended for detection of NUDT17 of human origin by WB, IP and ELISA