recommended for detection of Krox-26 of human origin by WB, IP and ELISA
Modification Notes
Krox-26, also known as ZNF22 (zinc finger protein 22), HKR-T1 or ZNF422, is a 224 amino acid protein that localizes to the nucleus and contains five CDH2-type zinc fingers. One of several members of the krueppel C2H2-type zinc-finger protein family, Krox-26 binds to DNA and is thought to be involved in transcriptional regulation events related to tooth formation, both in embryonic and adult tissue. The gene encoding Krox-26 maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPELISA
WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
recommended for detection of Krox-26 of human origin by WB IP and ELISA
Tissue Specificity
recommended for detection of Krox-26 of human origin by WB, IP and ELISA