| Product Name | gasdermin C Antibody (C-12) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping near the C-terminus of gasdermin C of human origin |
| Modification Notes | Gasdermin C (GSDMC), also known as melanoma-derived leucine zipper-containing extranuclear factor (MLZE), is a 508 amino acid member of the gasdermin protein family. Localized to the cytoplasm, gasdermin C is expressed primarily in spleen and trachea. Gasdermin C expression has been found to increase with the metastatic potential of melanoma cells. The gene that encodes gasdermin C maps to human chromosom 8, which encodes about 800 genes. Translocation of portions of chromosome 8 with amplifications of the c-Myc gene are found in some leukemias and lymphomas, and typically associated with a poor prognosis. Portions of chromosome 8 have been linked to schizophrenia and bipolar disorder. Chromosome 8 is also associated with Pfeiffer syndrome, congenital hypothyroidism and Waardenburg syndrome. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of gasdermin C of human origin by WB, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the C-terminus of gasdermin C of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the C-terminus of gasdermin C of human origin |
| Entrez Gene | 56169 |
|---|
| Application Notes | recommended for detection of gasdermin C of human origin by WB, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
