recommended for detection of TMPRSS11D of human origin by WB, IP, IF, IHC(P) and ELISA
Modification Notes
TMPRSS11D (transmembrane protease, serine 11D), also known as HAT, is a 418 amino acid single-pass type II membrane protein that contains one SEA domain and one peptidase S1 domain. Expressed in bronchi and trachea, TMPRSS11D functions as a monomer that cleaves the C-terminal side of arginine residues at the P1 position of certain peptides and, via this catalytic activity, plays a role in the host defense system. TMPRSS11D is inhibited by diisopropyl fluorophosphate, leupeptin, antipain and aprotinin and is subject to post-translational cleavage which results in the formation of an active, secreted peptide. The gene encoding TMPRSS11D maps to human chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFIHCELISA
WB:1:500~1:2000 IP:1:100~1:500 IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher.
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
recommended for detection of TMPRSS11D of human origin by WB IP IF IHC(P) and ELISA
Tissue Specificity
recommended for detection of TMPRSS11D of human origin by WB, IP, IF, IHC(P) and ELISA