| Product Name | ZNF397 Antibody (G-12) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping near the N-terminus of ZNF397 of human origin |
| Modification Notes | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF397 (zinc finger protein 397), also known as ZNF47 or ZSCAN15, is a 534 amino acid protein belonging to the krueppel C2H2-type zinc-finger protein family. Existing as three alternatively spliced isoforms, ZNF397 is expressed strongly in testis, moderately in skeletal muscle, pancreas and prostate, and weakly in heart, placenta, liver, kidney, spleen, thymus and small intestine. ZNF397 isoform 3 acts as a DNA-dependent transcriptional repressor. Isoforms 1 and 3 can both homo- and hetero-associate, however, homo-association of isoform 1 is dependent on the presence of the SCAN domain. ZNF397 contains nine C2H2-type zinc fingers and one SCAN box domain. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of ZNF397 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with other ZNF family members: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the N-terminus of ZNF397 of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the N-terminus of ZNF397 of human origin |
| Entrez Gene | 84307 |
|---|
| Application Notes | recommended for detection of ZNF397 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with other ZNF family members: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
