Application
Western blot analysis of ZNF161 expression in HeLa whole cell lysate.| Product Name | ZNF161 Antibody (H-166) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 351-516 mapping at the C-terminus of ZNF161 of human origin |
| Modification Notes | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF161, also called VEZF1 (vascular endothelial zinc finger 1) or DB1, is a nuclear localizing zinc-finger protein belonging to the Krüppel C2H2-type zinc-finger family. Expressed throughout the body with the highest level of expression found in the kidneys and skeletal muscle, ZNF161 is an endothelial transcription factor that regulates ET-1 (endothelin-1) promoter expression. Through its interaction with the CT/GC-rich region of the ET-1 promoter, ZNF161 helps to regulate proper assembly of the cardiovascular system during early development by activating the expression of various genes found in the vascular endothelium. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ZNF161 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 351-516 mapping at the C-terminus of ZNF161 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 351-516 mapping at the C-terminus of ZNF161 of human origin |
| Entrez Gene | 7716 |
|---|
Application
Western blot analysis of ZNF161 expression in HeLa whole cell lysate.| Application Notes | recommended for detection of ZNF161 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
