epitope mapping near the C-terminus of FAM123A of human origin
Modification Notes
The FAM123A (family with sequence similarity 123A) gene encodes for a 671 amino acid protein. There are two isoforms of FAM123A that exist as a result of alternative splicing events. The gene encoding FAM123A is located on chromosome 13, which comprises nearly 4% of human DNA and contains about 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. The gene SLITRK1, which is associated with Tourette syndrome, is on chromosome 13. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of FAM123A of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including porcine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping near the C-terminus of FAM123A of human origin
Tissue Specificity
epitope mapping near the C-terminus of FAM123A of human origin