| Product Name | ARL11 Antibody (E-15) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of ARL11 of human origin |
| Modification Notes | ADP-ribosylation factors (ARFs) are highly conserved guanine nucleotide binding proteins that enhance the ADP-ribosyltransferase activity of Cholera Toxin. ARF’s are important in eukaryotic vesicular trafficking pathways and they play an essential role in the activation of phospholipase D (PC-PLD). ARL11 (ADP-ribosylation factor-like 11), also known as ARLTS1 (ADP-ribosylation factor-like tumor suppressor protein 1), is a 196 amino acid protein that belongs to a family of ARF-like proteins. Expressed in leukocytes and lung tissue, ARL11 is thought to function as a tumor suppressor that may play a role in the regulation of apoptosis. Defects in the gene encoding ARL11 are associated with an increased susceptibility to chronic lymphocytic leukemia (CLL), melanoma and colorectal cancer. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of ARL11 of mouse, rat and human origin by WB, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of ARL11 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of ARL11 of human origin |
| Entrez Gene | 115761 |
|---|
| Application Notes | recommended for detection of ARL11 of mouse, rat and human origin by WB, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
