epitope mapping within an internal region of LOC729535 of human origin
Modification Notes
Comprising nearly 4% of human DNA, chromosome 13 contains around 114 million base pairs and 400 genes. Key tumor suppressor genes on chromosome 13 include the breast cancer susceptibility gene, BRCA2, and the RB1 (retinoblastoma) gene. RB1 encodes a crucial tumor suppressor protein which, when defective, leads to malignant growth in the retina and has been implicated in a variety of other cancers. The gene SLITRK1, which is associated with Tourette syndrome, is on chromosome 13. As with most chromosomes, polysomy of part or all of chromosome 13 is deleterious to development and decreases the odds of survival. Trisomy 13, also known as Patau syndrome, is quite deadly and the few who survive past one year suffer from permanent neurologic defects, difficulty eating and vulnerability to serious respiratory infections. The LOC729535 gene product has been provisionally designated LOC729535 pending further characterization.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of LOC729535 and C21orf70 of human origin by WB, IP, IF and ELISA also reactive with additional species, including equine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of LOC729535 of human origin
Tissue Specificity
epitope mapping within an internal region of LOC729535 of human origin
Application
Application
Western blot analysis of LOC729535 expression in COLO 320DM whole cell lysate.
Application Notes
recommended for detection of LOC729535 and C21orf70 of human origin by WB, IP, IF and ELISA also reactive with additional species, including equine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.