| Product Name | ASMT Antibody (N-20) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping at the N-terminus of ASMT of human origin |
| Modification Notes | Melatonin is a natually occurring secreted hormone that exhibits antioxidant capabilities and is crucial in the proper regulation of the circadian rhythm. ASMT (acetylserotonin O-methyltransferase), also known as HIOMT (hydroxyindole O-methyltransferase), is a 345 amino acid protein that belongs to the methyltransferase superfamily and is involved in melatonin biosynthesis. Expressed in brain, retina and pineal gland, ASMT functions to catalyze the final reaction in the synthesis of melatonin, specifically the conversion of S-adenosyl-L-methionine and N-acetylserotonin to S-adenosyl-L-homocysteine and melatonin. Multiple isoforms of ASMT exist due to alternative splicing events. The gene encoding ASMT maps to the pseudoautosomal region of chromosomes X and Y. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of ASMT of human origin by WB, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping at the N-terminus of ASMT of human origin |
|---|---|
| Tissue Specificity | epitope mapping at the N-terminus of ASMT of human origin |
| Entrez Gene | 438 |
|---|
| Application Notes | recommended for detection of ASMT of human origin by WB, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
