Application
Western blot analysis of INTS12 expression in Hela whole cell lysate.| Product Name | INTS12 Antibody (N-22) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of INTS12 of mouse and human origin by WB, IP and ELISA |
| Modification Notes | RNA polymerase II (Pol II) is an enzyme that is composed of twelve subunits and is responsible for the transcription of protein-coding genes. Transcription initiation requires Pol II-mediated recruitment of transcription machinery to a target promoter, thereby allowing transcription to begin. The integrator complex is a multi-protein complex that associates with the C-terminal domain of Pol II and is involved in small nuclear RNA (snRNA) transcription and 3’-end processing. INTS12 (Integrator complex subunit 12), also known as PHF22 (PHD finger protein 22), is a 462 amino acid protein that contains one PHD-type zinc finger and is a component of the integrator complex. Localized to the nucleus, INTS12 plays a role in the processing of select snRNAs and, via its PHD domain, mediates snRNA transcriptional regulation events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of INTS12 of mouse and human origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of INTS12 of mouse and human origin by WB, IP and ELISA |
| Entrez Gene | 57117 |
|---|
Application
Western blot analysis of INTS12 expression in Hela whole cell lysate.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
