Application
Western blot analysis of GDF-10 expression in A375 whole cell lysate.Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human cancer tissue showing cytoplasmic staining.| Product Name | GDF-10 Antibody (N-19) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of GDF-10 of human origin by WB, IP, IF, IHC(P) and ELISA |
| Modification Notes | Growth/differentiation factors (GDFs) are members of the TGF superfamily whose members are involved in embryonic development and adult tissue homeostasis. GDF-10 (growth differentiation factor 10), also known as BMP3B (Bone morphogenetic protein 3B) or BIP, is a 478 amino acid secreted protein that belongs to the TGF superfamily. Expressed in lung, femur, brain, testis, pancreas and skeletal muscle, GDF-10 exists as a homodimer or a heterodimer that, characteristic of BMP proteins, contains a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. GDF-10 is thought to play a role in cell growth and differentiation and may be involved in skeletal morphogenesis. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| WB:1:500~1:2000 IP:1:100~1:500 IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of GDF-10 of human origin by WB IP IF IHC(P) and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of GDF-10 of human origin by WB, IP, IF, IHC(P) and ELISA |
| Entrez Gene | 2662 |
|---|
Application
Western blot analysis of GDF-10 expression in A375 whole cell lysate.
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human cancer tissue showing cytoplasmic staining.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
