Application
Western blot analysis of ZNF446 expression in Hep G2 whole cell lysate.| Product Name | ZNF446 Antibody (B-18) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. As a member of the Krüppel C2H2-type zinc-finger protein family, ZNF446 (zinc finger protein 446), also known as Zinc finger and SCAN domain-containing protein 20 (ZKSCAN20), is a 450 amino acid transcriptional regulator. ZNF446 localizes to the nucleus and is expressed in a variety of human adult tissues with the highest expression level in muscle. ZNF446 contains three C2H2-type zinc fingers, a SCAN domain and a KRAB domain. ZNF446 functions as a transcriptional repressor for SRE (Serum Response Element) and c-Jun transcription factors and may play a critical role in cell growth and proliferation signaling pathways. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| recommended for detection of ZNF446 of human origin by WB, IP and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against ZNF446 of human origin |
|---|---|
| Tissue Specificity | raised against ZNF446 of human origin |
| Entrez Gene | 55663 |
|---|
Application
Western blot analysis of ZNF446 expression in Hep G2 whole cell lysate.| Application Notes | recommended for detection of ZNF446 of human origin by WB, IP and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
