Application
Western blot analysis of BTN1A1 expression in Hep G2 whole cell lysate.| Product Name | BTN1A1 Antibody (L-16) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | BTN1A1 (butyrophilin, subfamily 1, member A1), also known as BTN or BT, is a single-pass type I membrane protein that belongs to the BTN (butyrophilin)/MOG family of the immunoglobulin (Ig) superfamily. Localizing to the apical membrane and abundantly expressed in the secretory epithelium of the lactating mammary gland, BTN1A1 contains one B30.2/SPRY domain and two Ig-like V-type domains. BTN1A1 is secreted into milk as an integral membrane protein of fat droplets and plays a vital role in proper lipid secretion. Supporting its role in lipid secretion, BTN1A1 knockout mice exhibit accumulation of lipid in the mammary cells and secretion of large misshapen fat droplets. More specifically, BTN1A1 binds to Xanthine Oxidase, forming a complex that interacts with ADRP (adipophilin), thereby linking milk secretory granules to the plasma membrane and facilitating envelopment of the granule for secretion. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| recommended for detection of BTN1A1 of human origin by WB, IP and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against BTN1A1 of human origin |
|---|---|
| Tissue Specificity | raised against BTN1A1 of human origin |
| Entrez Gene | 696 |
|---|
Application
Western blot analysis of BTN1A1 expression in Hep G2 whole cell lysate.| Application Notes | recommended for detection of BTN1A1 of human origin by WB, IP and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
