Application
Western blot analysis of TES expression in non-transfected: (A) and mouse TES transfected: (B) 293T whole cell lysates.Application
Western blot analysis of TES expression in NIH/3T3 whole cell lysate.| Product Name | TES Antibody (H-95) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 304-398 mapping near the C-terminus of TES of human origin |
| Modification Notes | TES was originally identified as a candidate tumour suppressor gene and has been found to encode a novel focal adhesion protein called TES or Testin. TES localizes to cell-cell contacts, Actin stress fiber and interacts with a variety of cytoskeletal proteins including Zyxin, Mena, VASP, Talin and Actin. The ability of TES to associate with a-actinin, paxillin and Zyxin is dependent on the conformational state of the molecule. TES contains 3 LIM zinc-binding domains and may act as a tumor suppressor. Overexpression of the TES gene results in increased cell spreading and decreased cell motility. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Testin of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine, avian and feline: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 304-398 mapping near the C-terminus of TES of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 304-398 mapping near the C-terminus of TES of human origin |
| Entrez Gene | 26136 |
|---|
Application
Western blot analysis of TES expression in non-transfected: (A) and mouse TES transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of TES expression in NIH/3T3 whole cell lysate.| Application Notes | recommended for detection of Testin of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine, avian and feline: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
