| Product Name | Tor2 Antibody (y-155) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-155 mapping at the N-terminus of Tor2 of Saccharomyces cerevisiae origin |
| Modification Notes | Tor proteins, which encode putative phosphatidylinositol kinases, are involved in a signal transduction pathway in S. cerevisiae that activates cell wall expansion and protein synthesis in response to nutrient availability (1-3). Both Tor1 and Tor2 mediate protein synthesis via the phosphorylation of Tap42, which inhibits type-2A phosphatases (1,2,4,5). Tor1 and Tor2 also regulate G1 progression in yeast , and loss of Tor or treatment with rapamycin causes cells to arrest in early G1 (3-6). In addition to its overlapping function with Tor1, Tor2 is essential for the regulation of the cell-cycle-dependent organization of the actin cytoskeleton (5-7). The Tor signaling pathway is thought to mediate cell growth by harboring transcription factors in the cytoplasm, which mediate nutrient metabolism (2). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Tor2 of Saccaromyces cerevisiae origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-155 mapping at the N-terminus of Tor2 of Saccharomyces cerevisiae origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-155 mapping at the N-terminus of Tor2 of Saccharomyces cerevisiae origin |
| Application Notes | recommended for detection of Tor2 of Saccaromyces cerevisiae origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
