| Product Name | TRPV4 Antibody (H-79) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 62-134 mapping near the N-terminus of TRPV4 of human origin |
| Modification Notes | The transient receptor potential (TRP) protein family consists of a diverse group of cation channels functioning in a variety of homeostatic and regulatory pathways. Four subfamilies exist, based on channel domain homology, not activating stimuli: C type (canonical or classical), V type (vanilloid receptor related), M type (melastatin related) and P type (PKD). TRPV4, also designated VRL-2, TRP12, VR-OAC and OTRPC4, belongs to the V type subfamily, and plays a role in systemic osmoregulation. TRPV4 is a calcium channel activated by various stimuli, including thermal stress, fatty acid metabolites and hypotonicity. TRPV4 is highly expressed in lung and kidney. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of TRPV4 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 62-134 mapping near the N-terminus of TRPV4 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 62-134 mapping near the N-terminus of TRPV4 of human origin |
| Entrez Gene | 59341 |
|---|
| Application Notes | recommended for detection of TRPV4 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
