| Product Name | Proenkephalin B Antibody (M-248) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-248 representing full length Proenkephalin B of mouse origin |
| Modification Notes | The Proenkephalin precursor proteins are secreted proteins belonging to the opioid neuropeptide precursor family. The Proenkephalin proteins are proteolytically processed to form active secreted opioid peptides, which function as ligands for the ˚-type of opioid receptor. The Proenkephalin A precursor contains Synenkephalin, Leu-enkephalin and Met-enkephalin processed active peptides, while the Proenkephalin B precursor contains ∫-neoendorphin, Dynorphin, Leumorphin, Leu-enkephalin and rimorphin processed active peptides. ∫-endorphin and Met-enkephalin are endogenous opiates, while ACTH is crucial for adrenal gland stimulation to release cortisol. MSH increases melanin production in melanocytes, which leads to an increase in skin pigmentation. Leumorphin may be important in apoptosis prevention by being involved in the MAP kinase and PI 3-kinase pathways. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Proenkephalin B precusor and all processed active peptides of mouse and rat origin by WB, IP, IF and ELISA may cross-react with Proenkephalin A precursor: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-248 representing full length Proenkephalin B of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-248 representing full length Proenkephalin B of mouse origin |
| Entrez Gene | 18610 |
|---|
| Application Notes | recommended for detection of Proenkephalin B precusor and all processed active peptides of mouse and rat origin by WB, IP, IF and ELISA may cross-react with Proenkephalin A precursor: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
