| Product Name | LRTM2 Antibody (I-13) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Leucine-rich repeats (LRRs) are 20-30 amino acid motifs that mediate protein-protein interactions. The primary function of these motifs is to provide a versatile structural framework for the formation of these protein-protein interactions. LRRs are present in a variety of proteins with diverse structure and function, including innate immunity and nervous system development. Several human diseases are associated with mutations in the genes encoding LRR-containing proteins. LRTM2 (Leucine-rich repeat and transmembrane domain-containing protein 2) is a 370 amino acid single-pass type I membrane protein that contains six LRR repeats. The gene encoding LRTM2 maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of LRTM2 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with LRTM1 family member also reactive with additional species, including equine, canine, bovine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within a C-terminal cytoplasmic domain of LRTM2 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within a C-terminal cytoplasmic domain of LRTM2 of human origin |
| Entrez Gene | 654429 |
|---|
| Application Notes | recommended for detection of LRTM2 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with LRTM1 family member also reactive with additional species, including equine, canine, bovine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
