Application
Western blot analysis of LOXL4 expression in non-transfected: (A) and human LOXL4 transfected: (B) 293T whole cell lysates.| Product Name | LOXL4 Antibody (H-70) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 211-280 mapping within an internal region of LOXL4 of human origin |
| Modification Notes | Lysyl oxidase (LOX) proteins belong to a family of enzymes that oxidize primary amine substrated to reactive aldehydes. In fibrillar collagens and elastin, LOX catalyzes the lysine-derived cross-links of collagen fibrils and insoluble elastic fibers within the extracellular matrix. It can localize both to the nucleus and the cytoplasm. LOX is involved in tumor suppression, cell motility, cellular senescence and developmental regulation. There are four homologs of LOX, lysyl oxidase-like proteins designated LOX-like (LOXL1-LOXL4) proteins. LOXL4 is an extracellular protein that is widely expressed. Highest expression levels have been detected in testis, pancreas, cartilage and skeletal muscle. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of LOXL4 of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA also reactive with additional species, including canine and bovine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 211-280 mapping within an internal region of LOXL4 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 211-280 mapping within an internal region of LOXL4 of human origin |
| Entrez Gene | 84171 |
|---|
Application
Western blot analysis of LOXL4 expression in non-transfected: (A) and human LOXL4 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of LOXL4 of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA also reactive with additional species, including canine and bovine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
