| Product Name | ADAM4 Antibody (M-60) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 577-636 mapping near the C-terminus of ADAM4 of mouse origin |
| Modification Notes | ADAMs (disintegrin and metalloproteinase domain), also known as MDCs (metalloproteinase, disintegrin, and cysteine-rich domain) or cellular disintegrins are a family of proteins that are ubiquitously expressed. They catalyze proteolysis, adhesion, fusion and intracellular signaling. ADAMs are membrane-anchored, glycosylated, Zn2+ dependent proteases, and there are over 30 different members in the family with many diverse functions. ADAM1-6 localize to the testis, are developmentally regulated, and are involved in spermatogenesis and sperm-egg binding and fusion. ADAM4 expression occurs postmeiotically in spermatids. In addition to its expression in the testis, ADAM4 is also found at low levels in all other adult tissues. Peptides targeting the disintegrin domain of ADAM4 do not disturb spermatogenic cell attachment to Sertoli cell surfaces. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ADAM4 of mouse and rat origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 577-636 mapping near the C-terminus of ADAM4 of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 577-636 mapping near the C-terminus of ADAM4 of mouse origin |
| Entrez Gene | 11498 |
|---|
| Application Notes | recommended for detection of ADAM4 of mouse and rat origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
