Application
Western blot analysis of neuroglobin expression in non-transfected: (A) and human neuroglobin transfected: (B) 293T whole cell lysates.Application
Western blot analysis of neuroglobin expression in non-transfected: (A) and human neuroglobin transfected: (B) whole cell lysates.Application
Western blot analysis of neuroglobin expression in non-transfected: (A) and human neuroglobin transfected: (B) CHO whole cell lysates.Application
Western blot analysis of neuroglobin expression in non-transfected: (A) and human neuroglobin transfected: (B) 293 whole cell lysates.Application
Western blot analysis of human recombinant neuroglobin fusion protein.| Product Name | neuroglobin Antibody (FL-151) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-151 representing full length neuroglobin of human origin |
| Modification Notes | Globins are a superfamily of gas-binding heme proteins that are present in bacteria, protists, fungi, plants and animals. Globins play evolutionarily divergent roles which include binding, transport, scavenging, detoxification, and sensing of oxygen, nitric oxide and carbon monoxide. Neuroglobin (Ngb) is a hexacoordinate hemoglobin that is predominantly expressed in the vertebrate brain and may enhance oxygen supply to neural components. Neuroglobin displays a high affinity for oxygen and its presence in cerebral neurons suggests a role in neuronal responses to hypoxia or ischemia. For example, in vitro neuronal hypoxia causes an elevation in the levels of neuroglobin, which enhances neuronal cell survival. The human neuroglobin gene maps to chromosome 14q24 and encodes a 151 amino acid protein. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of neuroglobin of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-151 representing full length neuroglobin of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-151 representing full length neuroglobin of human origin |
| Entrez Gene | 58157 |
|---|
Application
Western blot analysis of neuroglobin expression in non-transfected: (A) and human neuroglobin transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of neuroglobin expression in non-transfected: (A) and human neuroglobin transfected: (B) whole cell lysates.
Application
Western blot analysis of neuroglobin expression in non-transfected: (A) and human neuroglobin transfected: (B) CHO whole cell lysates.
Application
Western blot analysis of neuroglobin expression in non-transfected: (A) and human neuroglobin transfected: (B) 293 whole cell lysates.
Application
Western blot analysis of human recombinant neuroglobin fusion protein.| Application Notes | recommended for detection of neuroglobin of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
