The tenascin family of extracellular matrix proteins includes Tenascin-C (also designated cytotactin or Tenascin), Tenascin-R (also designated restrictin, TN-R or janusin) and Tenascin-X. Tenascin proteins function as substrate-adhesion molecules (SAMs) and are involved in regulating numerous developmental processes, such as morphogenetic cell migration and organogenesis. The tenascin family proteins arise from various splicing events in the region of coding for FNIII repeats. Tenascin-C and Tenascin-X are expressed in several tissues during embryogenesis and in adult tissues undergoing active remodeling, such as healing wounds and tumors. Tenascin-R is expressed on the surface of neurons and glial cells.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of Tenascin-C of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and porcine
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 1601-1900 mapping near the C-terminus of Tenascin-C of human origin
Tissue Specificity
epitope corresponding to amino acids 1601-1900 mapping near the C-terminus of Tenascin-C of human origin
Western blot analysis of purified human Tenascin-C.
Application
Western blot analysis of Tenascin-C expression in Hs68 whole cell lysate.
Application Notes
recommended for detection of Tenascin-C of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine and porcine
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.