epitope corresponding to amino acids 35-334 mapping near the N-terminus of CEA (carcinoembryonic antigen) of human origin
Modification Notes
Carcinoembryonic antigen (CEA) is one of the most commonly used tumor markers in serum immunoassay determinations of carcinoma. Members of the CEACAM (carcinoembryonic antigen-related cell adhesion molecule) family contain a single N domain, with structural homology to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. CEACAMS, such as CEACAM1, CEACAM7, CD66C, CD66D and CD66E, have diverse roles within the cell, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. The human CEACAM proteins are encoded by genes which are located within a 1.2 Mb cluster on the long arm of chromosome 19.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
broadly reactive with CEA (CD66 isoforms) family members and CEA related molecules of human origin by WB, IP, IF and ELISA:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 35-334 mapping near the N-terminus of CEA (carcinoembryonic antigen) of human origin
Tissue Specificity
epitope corresponding to amino acids 35-334 mapping near the N-terminus of CEA (carcinoembryonic antigen) of human origin