| Product Name | pan cathepsin Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 34-333 mapping at the C-terminus of cathepsin L of human origin |
| Modification Notes | The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class includes cathepsins B, C, L, H, K, S, W and O. The aspartyl protease class consists of cathepsins D, E and F. Most cathepsins are lysosomal and each is involved in normal cellular metabolism, participating in various events such as peptide biosynthesis and protein degradation. Cathepsin J is a murine cysteine protease of the papain family expressed exclusively in the placenta, which may indicate a role in embryo implantation and/or placental function. Cathepsin L is a lysosomal cysteine protease that is most closely related to cathepsin H. Mouse cathepsin M is closely related to cathepsins P and L and is highly expressed in placenta. Cathepsins M, P, Q, and R, are conserved in mice and rats but not found in human or rabbit placenta, showing that this family of proteases are probably restricted to rodents. Cathepsin V, also known as Cathepsin U or Cathepsin L2, is mostly expressed in the thymus and testis and may be involved in tumor processes. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of cathepsin J, L, M, P, Q, R, U and V of mouse, rat and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 34-333 mapping at the C-terminus of cathepsin L of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 34-333 mapping at the C-terminus of cathepsin L of human origin |
| Entrez Gene | 1514 |
|---|
| Application Notes | recommended for detection of cathepsin J, L, M, P, Q, R, U and V of mouse, rat and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
